Why Choose Wecaps Empty Enteric Coated Capsules?

In the pharmaceutical industry, the reliability of drug delivery systems cannot be ignored. Enteric coated capsules, a specialized form of oral dosage form, have gained significant attention for their ability to protect sensitive drug ingredients from the harsh acidic environment of the stomach, ensuring they reach the intestine for optimal absorption. In this blog post, Wecaps will share with you the features of empty enteric coated capsules, the key components for producing effective and safe drugs.

The Science Behind Enteric Coating:

Enteric coatings are designed to resist stomach acid, keeping the capsules intact until they reach the alkaline environment of the small intestine. They are usually made of polymers such as hydroxypropyl methylcellulose (HPMC) or gelatin, which have been shown to be biocompatible and safe for humans.

Enteric coated capsules remain stable in gastric fluid and only break down in the intestine, ensuring that the active pharmaceutical ingredient safely reaches the target area, ensuring efficacy. This targeted release can reduce drug irritation to the gastric mucosa, minimizing potential gastric discomfort and side effects.

Quality Control and Management:

The production of empty enteric coated capsules is subject to stringent quality control measures. Manufacturers like Wecaps adhere to Good Manufacturing Practice (GMP) standards, ensuring that every capsule is produced in a controlled environment with consistent temperature and humidity. This meticulous attention to detail is vital for maintaining the structural integrity and performance of the capsules.

Raw Material Inspection and Preparation:

The journey of an enteric coated capsule begins with the inspection of raw materials. High-quality gelatin or plant-based materials are selected, ensuring they meet pharmaceutical-grade standards. The preparation process involves the use of stainless steel reactors, which are crucial for maintaining the purity and quality of the gelatin or HPMC base.

Automated Production and Inspection:

State-of-the-art automatic capsule production lines are employed to manufacture the capsules with precision. Post-production, an automatic capsule sorting machine inspects each capsule for defects, ensuring that only those meeting the highest quality standards proceed to packaging. Ultimately, our capsules are of standard size, without holes, spots or scratches, and have an extremely low breakage rate, greatly reducing capsule shell waste.

Customization and Technical Support:

Wecaps offers customization services, allowing pharmaceutical companies to select capsule colors and print customer logos, enhancing brand recognition and product differentiation. Technical support is also provided, with experts advising on the choice of materials and sizes to suit specific pharmaceutical needs.

Storage and Packaging:

Proper storage is essential for maintaining the stability of empty enteric coated capsules. Wecaps employs moisture control methods, ensuring that the capsules are stored in an environment with a humidity level between 12.5% and 17.5%. The storage areas are kept clean, dust-free, and well-ventilated, with a temperature range of 15-25°C to preserve the capsules' optimal texture and structure.

As the demand for targeted drug delivery systems continues to grow, the role of Wecaps in the development of effective drug products becomes increasingly important through focus on precise enteric release, diverse material selection and strict quality control, and the capsules produced by Wecaps can meet the dynamic needs of the healthcare industry.

About Wecaps:

Wecaps is a leading supplier of enteric coated capsules, committed to providing high-quality products that meet the diverse needs of the pharmaceutical industry. With a global business footprint, registered with the U.S. FDA, and listed in the EU IMSOC product directory, Wecaps is a trusted partner for major pharmaceutical companies worldwide.